Catalytic asymmetric deprotonation of phosphine boranes and sulfides as a route to P-stereogenic compounds.
نویسندگان
چکیده
A comparison between phosphine boranes and sulfides in their catalytic asymmetric deprotonation using organolithiums and sub-stoichiometric amounts of (-)-sparteine has revealed superior catalytic efficiency in the phosphine sulfide deprotonation.
منابع مشابه
Simple unprecedented conversion of phosphine oxides and sulfides to phosphine boranes using sodium borohydride.
A variety of phosphine oxides and sulfides can be efficiently converted directly to the corresponding phosphine boranes using oxalyl chloride followed by sodium borohydride. Optically active P-stereogenic phosphine oxides can be converted stereospecifically to phosphine boranes with inversion of configuration by treatment with Meerwein's salt followed by sodium borohydride.
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ورودعنوان ژورنال:
- Chemical communications
دوره 32 شماره
صفحات -
تاریخ انتشار 2008